Single prolonged stress disrupts retention of extinguished fear in rats
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چکیده
منابع مشابه
Effects of β-Estradiol on Enhanced Conditioned Fear Induced by Single Prolonged Stress and Shock in Rats
Introduction:This study examined the effects of administration of subcutaneous β-estradiol on PTSD-like symptoms (the enhanced conditioned fear response, CFR) that induced by a single-prolonged stress (SPS) and shock in rats. Adult male Wistar rats were exposed to SPS procedure: restraint for 2 h, forced swim for 20 min, and ether anesthesia. Then the rats were placed in fear conditioning syste...
متن کاملReinstatement of an extinguished fear conditioned response in infant rats.
Although it is currently accepted that the extinction effect reflects new context-dependent learning, this is not so clear during infancy, because some studies did not find recovery of the extinguished conditioned response (CR) in rodents during this ontogenetic stage. However, recent studies have shown the return of an extinguished CR in infant rats. The present study analyzes the possibility ...
متن کاملeffects of β-estradiol on enhanced conditioned fear induced by single prolonged stress and shock in rats
introduction:this study examined the effects of administration of subcutaneous β-estradiol on ptsd-like symptoms (the enhanced conditioned fear response, cfr) that induced by a single-prolonged stress (sps) and shock in rats. adult male wistar rats were exposed to sps procedure: restraint for 2 h, forced swim for 20 min, and ether anesthesia. then the rats were placed in fear conditioning syste...
متن کاملInduced by Single Prolonged Stress and Shock in Rats
ost-traumatic stress disorder (PTSD) is a psychiatric disorder, which can occur following the experience or witnessing of life-threatening events such as terrorist incidents, military combat, natural disasters, serious accidents, or violent personal assaults. Symptoms of PTSD may include reliving the experience through # $ = % # " # and feeling detached or estranged (Breslau, Davis, Induced by ...
متن کاملStress disrupts the reconsolidation of fear memories in men.
Reconsolidation is a post-retrieval process of restabilization of the memory trace. Previous findings from our group suggest that cortisol, a glucocorticoid hormone secreted in response to stress, enhances the reconsolidation of fear memories in healthy men. Cortisol effect was found to be very specific, enhancing only the fear memory that was reactivated (i.e. retrieved), but not the non-react...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2012
ISSN: 1072-0502,1549-5485
DOI: 10.1101/lm.024356.111